Our developmental model, characterized by drastic gene expression changes, is the organogenesis at Arabidopsis shoot apex, which is governed by major nuclear reprograming events that determine stem cell fates.
We use an integrative approach connecting developmental processes, transcriptomes/epigenomes and molecular/atomic properties of individual protein regulators and complexes. For this, we combine our expertise in plant molecular genetics and chromatin biology with local skills and infrastructures for biochemistry, biophysics and structural biology.